P-341 Endometrial compaction and its impact on reproductive outcome

Abstract Study question Is there a relationship between endometrial compaction and clinical pregnancy rate in frozen embryo transfer (FET) cycles? Summary answer Clinical (CPR) were similar both patients that demonstrated or no FETs cycles. What is known already There has been increasing interest the correlation outcomes but conflicting evidence from prior investigations. design, size, duration Retrospective Observational data Analysis of (n-350) undergoing Embryo Transfer during January 2022 to December at our clinic. Participants/materials, setting, methods This study was performed single, academically affiliated fertility center which who had an FET using programmed/modified natural cycle protocol included. Endometrial thickness time start progesterone(T1)(TVS) & (T2)(TAS)was measured, percentage on ET HRT modified studied. The primary outcome based proportion (percentage difference EMT T1 T2). Main results role chance Of 350 participants included, 64%, 38% and10%, women exhibited >0%, >5% >10% compaction, respectively. not predictive Pregnancy Rate any defined cutoffs .Primary included CPR (defined as presence least one gestational sac with fetal pole cardiac activity transvaginal ultrasound 6 9 weeks gestation), biochemical spontaneous abortion rate. Patients discharged their obstetrician when confirmed gestation. Limitations, reasons for caution potential measurement error recorded EMTs. T2 transabdominally, may cause error, it generally accepted measurements are more accurate, though, bias expected be non-differential Wider implications findings Assessing lead unnecessary cancellation. However, further studies needed determine if routine screening would improve outcomes. Trial registration number applicable